• Advanced heart failure: a position statement of the Heart Failure Association of the European Society of Cardiology 

      Crespo-Leiro, María Generosa; Metra, Marco; Lund, Lars H.; Milicic, Davor; Costanzo, Maria Rosa; Filippatos, Gerasimos; Gustafsson, Finn; Tsui, Steven; Barge-Caballero, Eduardo; De Jonge, Nicolaas; Frigerio, Maria; Hamdan, Righab; Hasin, Tal; Hülsmann, Martin; Nalbantgil, Sanem; Potena, Luciano; Bauersachs, Johann; Gkouziouta, Aggeliki; Ruhparwar, Arjang; Ristic, A.D.; Straburzynska-Migaj, Ewa; McDonagh, Theresa; Seferovic, Petar M.; Ruschitzka, Frank (Wiley, 2018-05-27)
      [Abstract] This article updates the Heart Failure Association of the European Society of Cardiology (ESC) 2007 classification of advanced heart failure and describes new diagnostic and treatment options for these patients. ...
    • Advanced heart failure: definition, epidemiology, and clinical course 

      Crespo-Leiro, María Generosa; Barge-Caballero, Eduardo (Elsevier, 2021-07-15)
      [Abstract] Advanced heart failure (HF) is characterized by a progressive worsening of symptoms disabling for daily life, refractory to all therapies, and with high mortality. These patients may be candidates for life-prolonging ...
    • AGT haplotype in ITGA4 gene is related to antibody-mediated rejection in heart transplant patients 

      Núñez, Lucía; Marrón Liñares, Grecia Manuela; Crespo-Leiro, María Generosa; Barge-Caballero, Eduardo; Álvarez López, Eloy; Suárez-Fuentetaja, Natalia; Paniagua-Martín, María J.; Pombo-Otero, Jorge; Muñiz, Javier; Tan, Carmela D.; Rene Rodríguez, E.; Vázquez Rodríguez, José Manuel (Stanislaw Stepkowski,, 2019-07-23)
      [Abstract] Introduction. One of the main problems involved in heart transplantation (HT) is antibody-mediated rejection (AMR). Many aspects of AMR are still unresolved, including its etiology, diagnosis and treatment. ...
    • Analysis of variants in the HCN4 gene and in three single nucleotide polymorphisms of the CYP3A4 gene for association with ivabradine reduction in heart rate: a preliminary report 

      Núñez, Lucía; Crespo-Leiro, María Generosa; Marrón Liñares, Grecia Manuela; Suárez-Fuentetaja, Natalia; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Grille Cancela, Zulaika; Muñiz, Javier; Vázquez Rodríguez, José Manuel; Hermida-Prieto, Manuel (Via Médica, 2016)
      [Abstract] Background: Ivabradine, a selective bradycardic drug, inhibits the If. In patients with heart failure (HF), ivabradine reduces the risk of rehospitalization and mortality. The average heart rate (HR) reduction ...
    • Axillary implantation of Impella CP allows early rehabilitation of patients in cardiogenic shock bridged to heart transplantation 

      Couto-Mallón, David; Estévez-Cid, Francisco; Velasco-García, Carlos; Herrera-Noreña, José M.; Iglesias-Gil, Carmen; Solla-Buceta, Miguel; Seoane-Quiroga, L.; Aller-Fernández, V.; Fojón, S.; Balsa-Canto, M.; Barge-Caballero, Eduardo; Barge-Caballero, Gonzalo; Paniagua-Martín, María J.; Crespo-Leiro, María Generosa; Cuenca-Castillo, José J. (Wiley, 2017-05)
    • Beta-blocker exposure and survival in patients with transthyretin amyloid cardiomyopathy 

      Barge-Caballero, Gonzalo; Barge-Caballero, Eduardo; López-Pérez, Manuel; Bilbao-Quesada, Raquel; González-Babarro, Eva; Gómez-Otero, Inés; López-López, Andrea; Gutiérrez-Feijoo, Mario; Varela-Román, Alfonso; González-Juanatey, Carlos; Díaz-Castro, Óscar; Crespo-Leiro, María Generosa (Elsevier, 2022-02)
      [Abstract] Objective: To investigate a potential association between beta-blocker exposure and survival in patients with transthyretin amyloid cardiomyopathy (ATTR-CM). Methods: In this real-world prospective registry ...
    • Cancer in patients with heart failure: incidence, risk factors and prognostic impact 

      Sagastagoitia-Fornie, Marta; Barge-Caballero, Eduardo; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Enríquez-Vázquez, Daniel; Blanco-Canosa, Paula; Grille-Cancela, Zulaika; Jiménez-Navarro, Manuel; Muñiz, Javier; Vázquez-Rodríguez, José M.; Crespo-Leiro, María Generosa (Elsevier, 2022-09-16)
      [Abstract] Aims: To assess the incidence of cancer diagnosis and cancer-related mortality in patients with heart failure (HF). Methods: Observational study based in a prospective cohort of patients with HF referred to ...
    • Cardiac amyloidosis: description of a series of 143 cases 

      Barge-Caballero, Gonzalo; Barge-Caballero, Eduardo; López-Pérez, Manuel; Bilbao-Quesada, Raquel; González-Babarro, Eva; Gómez-Otero, Inés; López-López, Andrea; Gutiérrez-Feijoo, Mario; Varela-Román, Alfonso; González-Juanatey, Carlos; Díaz-Castro, Óscar; Crespo-Leiro, María Generosa (Elsevier, 2022-09-09)
      [Abstract] Introduction and objectives: Recently, there have been important advances in the diagnosis and treatment of cardiac amyloidosis (CA). Our aim was to provide an updated description of its 2 most frequent types: ...
    • Chronic anemia in heart transplant patients: prevalence, risk factors, and prognostic significance 

      Cursack, Guillermo C.; Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Muñiz, Javier; Naya, Carmen; Grille Cancela, Zulaika; Rodríguez-Fernández, José Ángel; Marzoa Rivas, Raquel; Barge-Caballero, Eduardo; Ríos, Ramón; Estévez, Francisco; Cuenca, José J.; Juffé-Stein, Alberto; Castro-Beiras, Alfonso (Elsevier, 2007)
      [Abstract] Introduction and objectives. Data on chronic anemia following heart transplantation (HT) are scarce and contradictory. Our aims were to determine the prevalence of chronic anemia after HT, to identify predisposing ...
    • Circulating Galectin-3 Following Heart Transplant: Long-term Dynamics and Prognostic Value 

      Suárez-Fuentetaja, Natalia; Barge-Caballero, Eduardo; Bayés-Genís, Antoni; Doménech, Nieves; Moreda-Santamaría, Lucía; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Solla-Buceta, Miguel; Estévez-Cid, Francisco; Cuenca-Castillo, José J.; Pombo-Otero, Jorge; Grille-Cancela, Zulaika; Blanco-Canosa, Paula; Muñiz, Javier; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2018-11-23)
      [Abstract] Introduction and objectives: Circulating galectin-3 (Gal-3) is elevated and significantly correlates with all-cause and cardiovascular mortality in patients with heart failure. However, the relationship between ...
    • Circulating miR-181a-5p as a New Biomarker for Acute Cellular Rejection in Heart Transplantation 

      Constanso-Conde, Ignacio; Hermida-Prieto, Manuel; Barge-Caballero, Eduardo; Núñez, Lucía; Pombo-Otero, Jorge; Suárez-Fuentetaja, Natalia; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Pan Lizcano, Ricardo Francisco; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2020-06-07)
      [Abstract] Background: Acute cellular rejection (ACR) is a major complication in heart transplantation (HTx). Endomyocardial biopsy is the reference method for early detection of ACR, but a new non-invasive approach is ...
    • Clinical Characteristics and Long-term outcomes of patients undergoing combined heart-kidney transplantation: a single-center experience 

      López-Sainz, A.; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Sánchez-Fernández, G.; Fernández Arias, L.; García-Vieites, M.; Alonso-Hernández, Á.; Rodríguez-Rivera-García, J.J.; Crespo-Leiro, María Generosa (Elsevier, 2015-01-30)
      [Abstract] Background. The purpose of the study was to describe clinical characteristics and long-term survival of patients undergoing combined heart-kidney transplant in a single center. Methods. We conducted a retrospective ...
    • Clinical evaluation of rosuvastatin in heart transplant patients with hypercholesterolemia and therapeutic failure of other statin regimens: short-term and long-term efficacy and safety results 

      Barge-Caballero, Gonzalo; Barge-Caballero, Eduardo; Marzoa Rivas, Raquel; Paniagua-Martín, María J.; Barrio-Rodríguez, Alfredo; Naya, Carmen; Blanco-Canosa, Paula; Grille Cancela, Zulaika; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Wiley, 2015-04-23)
      [Abstract] We conducted an observational study of 30 heart transplant recipients with serum low-density lipoprotein cholesterol (LDL-c) >100 mg/dl despite previous statin therapy, who were treated with rosuvastatin 10 mg ...
    • Clinical outcomes in heart transplant recipients with coronary abnormalities in the donor graft 

      Fernández de-Aspe, Pablo; Barge-Caballero, Eduardo; Aldama López, Guillermo; Fernández-Arias, Laura; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2023-02-02)
    • Clinical Profile and Causes of Death According to Ejection Fraction in Patients With Heart Failure Cared for in a Specialized Cardiology Unit 

      Barge-Caballero, Eduardo; Montero-Fole, B.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Pardo-Martínez, Patricia; Sagastagoitia-Fornie, Marta; Muñiz, Javier; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2021-05-14)
      [Abstract] Background and objective. Patients with heart failure are classified into three phenotypes based on left ventricular ejection fraction. This work aimed to compare the clinical profile, treatment, prognosis, ...
    • Comparison of predicted and observed mortality in patients with heart failure treated at a specialized unit 

      Barge-Caballero, Eduardo; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Marzoa-Rivas, Raquel; Naya-Leira, Carmen; Riveiro-Rodríguez, Cristina M.; Grille-Cancela, Zulaika; Blanco-Canosa, Paula; Muñiz, Javier; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2020-01-21)
      [Abstract] Introduction and objectives: To analyze survival in heart failure (HF) patients treated at a specialized unit. Methods: Prospective cohort-based study of HF patients treated at a specialized unit from 2011 ...
    • Determinants and prognostic value of peak oxygen uptake in the current era of heart failure disease modifying therapy 

      Roibal-Pravio, J.; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Martínez-Ruiz, D.; Fábregas-Casal, R.; Blanco-Canosa, Paula; Naya, Carmen; Riveiro-Rodríguez, C.M.; Grille Cancela, Zulaika; Costa-Grana, C.M.; Pérez-Fernández, R.; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Wiley, 2017-05-01)
    • Determinants of Maximal Oxygen Uptake in Patients With Heart Failure 

      Roibal-Pravio, J.; Barge-Caballero, Eduardo; Barbeito Caamaño, Cayetana; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Pardo-Martínez, Patricia; Grille Cancela, Zulaika; Blanco-Canosa, Paula; García-Pinilla, José Manuel; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Wiley Online Library, 2021-03-27)
      [Abstract] Aims Maximum oxygen uptake (VO₂max) is an essential parameter to assess functional capacity of patients with heart failure (HF). We aimed to identify clinical factors that determine its value, as they have not ...
    • Empleo del balón de contrapulsación intraaórtico como puente al trasplante cardiaco en España: resultados del estudio ASIS-TC 

      Barge-Caballero, Eduardo; González-Vílchez, Francisco; Delgado, Juan F.; Mirabet-Pérez, Sonia; González-Costello, José; Pérez-Villa, Félix; Martínez-Sellés, Manuel; Segovia-Cubero, Javier; Hervás-Sotomayor, Daniela; Blasco-Peiró, Teresa; De la Fuente-Galán, Luis; Garrido-Bravo, Iris P.; Rábago-Juan-Aracil, Gregorio; Muñiz, Javier; Crespo-Leiro, María Generosa (Elsevier, 2018)
      [Resumen] Introducción y objetivos. En España, el balón de contrapulsación intraaórtico (BCIA) se ha usado frecuentemente como puente al trasplante cardiaco (TxC) urgente. El propósito es analizar los resultados de esta ...
    • Epidemiological study of tricuspid regurgitation after cardiac transplantation: does it influence survival? 

      López-Vilella, Raquel; Paniagua-Martín, María J.; González-Vílchez, Francisco; Donoso Trenado, Víctor; Barge-Caballero, Eduardo; Sánchez-Lázaro, Ignacio; Aller Fernández, Ana Vanesa; Martínez-Dolz, Luis; Crespo-Leiro, María Generosa; Almenar-Bonet, Luis (Frontiers, 2022-03-21)
      [Abstract] Background: Tricuspid valve disease is the most frequent valvulopathy after heart transplantation (HTx). Evidence for the negative effect of post-transplant tricuspid regurgitation (TR) on survival is contradictory. ...